Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents

Hüseyin Taştanoğlu; Nurullah Çelik

doi:10.7197/cmj.1022934

EN

Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents

Abstract

Objective: There is a lot of study in adults investigating the Triglyceride-Glucose (Ty-G) index. However, a limited study has been searched in the pediatric age group. Moreover, to the best of our knowledge, there is no study on Turkish children. The aim of this study, to investigate the usability of the triglyceride-glucose index as an indicator of insulin resistance in obese adolescents and to calculate the cut-off values.

Method: Six hundred twenty-three pubertal obese adolescents (266 boys, and 357 girls) were retrospectively evaluated. Ty-G index and HOMA-IR levels were calculated. ROC analysis was used for the estimations of the Ty-G index cutoff value.

Results: There was positive correlation between HOMA-IR and Ty-G index in boys (r=0.255, p<0.001), in girls (r=0.402, p<0.001), and all study groups (r=0.323, p<0.001). Ty-G index cutoff value for insülin resistance in pubertal obese adolescents was calculated as 8.42 with 70.1 % sensitivity and 59.3 % specificity for all study groups; 8,38 with 71.1 % sensitivity, and 48.3 % specificity for boys; 8,27 with 80% sensitivity, and 52.9% specificity for girls.

Conclusions: Ty-G index may be a reliable indicator for insülin resistance in pubertal obese adolescents. More attention should be given fort his marker with prospective studies.

Keywords

Supporting Institution

Retrospektif bir çalışma olup destekleyen bir kurum yok

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Hüseyin Taştanoğlu
0000-0002-6034-9998
Türkiye

Nurullah Çelik ^*
0000-0003-1583-6807
Türkiye

Publication Date

December 31, 2021

Submission Date

November 13, 2021

Acceptance Date

December 9, 2021

Published in Issue

Year 2021 Volume: 43 Number: 4

DOI

https://doi.org/10.7197/cmj.1022934

IZ

https://izlik.org/JA67CF82DC

Cite

RIS / Bibtex

AMA

1.Taştanoğlu H, Çelik N. Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents. CMJ. 2021;43(4):355-363. doi:10.7197/cmj.1022934

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Journal of Biotechnology and Strategic Health Research

https://doi.org/10.34084/bshr.1311813

Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents

Abstract

Keywords

Öz

Supporting Institution

References

Details

Primary Language

Subjects

Journal Section

Authors

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Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite

Cited By

EVALUATION OF INSULIN RESISTANCE IN PATIENTS WITH PREMATURE ADRENARCHE

Triglyceride-Glucose Index is a novel predictor of colorectal cancer