Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents

Hüseyin Taştanoğlu; Nurullah Çelik

doi:10.7197/cmj.1022934

EN

Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents

Abstract

Objective: There is a lot of study in adults investigating the Triglyceride-Glucose (Ty-G) index. However, a limited study has been searched in the pediatric age group. Moreover, to the best of our knowledge, there is no study on Turkish children. The aim of this study, to investigate the usability of the triglyceride-glucose index as an indicator of insulin resistance in obese adolescents and to calculate the cut-off values.

Method: Six hundred twenty-three pubertal obese adolescents (266 boys, and 357 girls) were retrospectively evaluated. Ty-G index and HOMA-IR levels were calculated. ROC analysis was used for the estimations of the Ty-G index cutoff value.

Results: There was positive correlation between HOMA-IR and Ty-G index in boys (r=0.255, p<0.001), in girls (r=0.402, p<0.001), and all study groups (r=0.323, p<0.001). Ty-G index cutoff value for insülin resistance in pubertal obese adolescents was calculated as 8.42 with 70.1 % sensitivity and 59.3 % specificity for all study groups; 8,38 with 71.1 % sensitivity, and 48.3 % specificity for boys; 8,27 with 80% sensitivity, and 52.9% specificity for girls.

Conclusions: Ty-G index may be a reliable indicator for insülin resistance in pubertal obese adolescents. More attention should be given fort his marker with prospective studies.

Keywords

Destekleyen Kurum

Retrospektif bir çalışma olup destekleyen bir kurum yok

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Sağlık Kurumları Yönetimi

Bölüm

Araştırma Makalesi

Yazarlar

Hüseyin Taştanoğlu
0000-0002-6034-9998
Türkiye

Nurullah Çelik ^*
0000-0003-1583-6807
Türkiye

Yayımlanma Tarihi

31 Aralık 2021

Gönderilme Tarihi

13 Kasım 2021

Kabul Tarihi

9 Aralık 2021

Yayımlandığı Sayı

Yıl 2021 Cilt: 43 Sayı: 4

DOI

https://doi.org/10.7197/cmj.1022934

IZ

https://izlik.org/JA67CF82DC

Kaynak Göster

RIS / Bibtex

AMA

1.Taştanoğlu H, Çelik N. Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents. CMJ. 2021;43(4):355-363. doi:10.7197/cmj.1022934

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EVALUATION OF INSULIN RESISTANCE IN PATIENTS WITH PREMATURE ADRENARCHE

Turkish Journal of Science and Health

https://doi.org/10.51972/tfsd.1144735

Triglyceride-Glucose Index is a novel predictor of colorectal cancer

Journal of Biotechnology and Strategic Health Research

https://doi.org/10.34084/bshr.1311813

Triglyceride-Glucose index as a surrogate marker for insulin resistance in obese adolescents

Abstract

Keywords

Öz

Destekleyen Kurum

Kaynakça

Ayrıntılar

Birincil Dil

Konular

Bölüm

Yazarlar

Yayımlanma Tarihi

Gönderilme Tarihi

Kabul Tarihi

Yayımlandığı Sayı

DOI

IZ

Kaynak Göster

Cited By

EVALUATION OF INSULIN RESISTANCE IN PATIENTS WITH PREMATURE ADRENARCHE

Triglyceride-Glucose Index is a novel predictor of colorectal cancer