Recurrent Aphthous Stomatitis and Related Factors in Turkish Adult Population: A Striking Outcome of Cappadocia Chronic Diseases Epidemiological Study
Abstract
Methods: In 2013, by the Turkish Society of Internal Medicine, a cohort for chronic diseases and related risk factors was initiated in the Central Anatolia Region of Turkey (Cappadocia region). 90% of the whole adult population was included and photos of oral aphthae were used during the questionnaire for chronic diseases.
Results: 10 992 participants, aged ≥18 years included. The mean age were 44.6± 16.4 years; 56.1% were males. RAS history was present in 13.2%, more frequent in females (17.1%). Female gender ( OR: 1.441, CI: 1.253-1.656, p<0.001), presence of any rheumatic disease (OR: 2.364, CI: 1.408-3.968, p:0.001), history of joint swelling (OR: 1.755, CI: 1.527-2.016, p<0.001), low back pain history (OR: 1.727, CI:1.529-1.952, p<0.001) were independent risk factors for RAS. Age (OR: 0.994, CI: 0.990-0.997, p:0.001), alcohol usage (OR: 0.744, CI: 0.566-0.977, p: 0.033) and smoking (OR: 0.651, CI: 0.555-0.763, p<0.001) were protective for RAS.
Conclusions: RAS prevalence was 13.2% in our population-based cohort. Underlying inflammatory rheumatic diseases must be searched in the case of RAS. Alcohol may have a reducing effect on RAS, needs further evaluation.
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Supporting Institution
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Authors
Umut Kalyoncu
0000-0001-7129-2109
Türkiye
Omer Karadag
0000-0001-6807-5066
Türkiye
Ali Akdoğan
0000-0001-7592-3844
Türkiye
Abdulsamet Erden
0000-0002-8084-2018
Türkiye
Levent Kılıç
0000-0002-3102-5847
Türkiye
Şule Apraş Bilgen
0000-0001-8208-1585
Türkiye
İhsan Ertenli
0000-0002-3904-0769
Türkiye
Sedat Kiraz
0000-0003-2802-6061
Türkiye
Publication Date
October 1, 2022
Submission Date
March 3, 2022
Acceptance Date
September 26, 2022
Published in Issue
Year 2022 Volume: 44 Number: 3