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Analyzing The Relationship Between Systemic Inflammatory Index, Neutrophil Lymphocyte Ratios And Covid-19 Infection
Abstract
Introduction: There are important parameters in understanding the severity of COVID-19 infection. We aimed to observe the role of systemic inflammatory index and neutrophil lymphocyte ratios in Covid-19 infections and the changes seen during the infection process.
Method: This retrospective single-center study was conducted between April 2020 and May 2020. Clinical, demographic and laboratory data of patients with COVID-19 were analyzed. All COVID-19 case confirmation made with reverse transcription polymerase chain reaction. Neutrophil/lymphocyte ratio and SII change and relationship were examined.
Results: 140 patients were included in our study and 50 of them were female. There was no statistically significant difference in SII according to gender (p>0.05) but there was a difference in SII between age categories (p=0.009). A statistically significant difference was found (p=0.003) regardless of the presence of comorbidities. Tobacco users had a significantly lower SII (p=0.028). A statistically significant difference was found between SII and Covid Severity Index (p=0.020). A statistically significant difference was found in the SII values of those receiving favipiravir treatment and those receiving hydroxychloroquine treatment (p<0.001). A statistically significant difference was found between those who received treatment in the outpatient clinic and those who received treatment in the intensive care unit (p=0.043). A statistically significant difference in the SII values was found between the patients who died and those who survived (p= 0.009).
Conclusion: The Systemic Inflammatory Index is a parameter that can be used for the Covid-19 patient follow-up and estimating mortality.
Keywords
Supporting Institution
yok
Project Number
yok
References
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Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Early Pub Date
June 30, 2023
Publication Date
June 30, 2023
Submission Date
January 21, 2023
Acceptance Date
June 9, 2023
Published in Issue
Year 2023 Volume: 45 Number: 2