EN
Did Covid 19 disease increase mesenteric ischemia cases?
Abstract
İntroduction
Covid 19 (C19) disease causes mortal complications due to both respiratory system involvement and extrapulmonary involvement. C19 patients may present with gastrointestinal symptoms such as nausea-vomiting, diarrhea and loss of appetite, as well as serious conditions such as acute mesenteric ischemia. C19 disease is a proinflammatory condition that causes thrombus formation.
Material method
The first group (G1) was treated with 21 mesenteric ischemia cases operated in the General Surgery Department of Aksaray Training and Research Hospital in approximately two years between March 2020 and February 2022, and the second group (G2), in a two-year period between 2018-2020 before the pandemic, in the same department. The information of 11 mesenteric ischemia cases who underwent surgery were analyzed from the hospital information system. Statistically, the predisposing diseases, demographic data, intestinal lengths removed during the operation, and survival of the patients in both groups were compared.
Results
When the number of patients who were operated on in G1 and G2 were compared, it was seen that more patients were operated in G1. The probability of mesenteric ischemia in a 24-month period was found to be 0.875 in G1 and 0.458 in G2. These rates were statistically different (p=0.002). When the mean age, length of the removed bowel, and postoperative mortality of both groups were compared, no significant difference was found.
Conclusion
Although the exact mechanism by which the Covid 19 disease causes mesenteric ischemia is not understood, we observed a statistically significant increase in mesenteric ischemia cases during the pandemic period compared to the pre-pandemic return. Considering the Physiopathology of C19, it is known that the diseases in the body generally occur on the basis of vasculitis. When C19 infection is detected, we recommend anticoagulant treatment for at least 3 months during the infection and for the prevention of other complications related to vasculitis, especially mesenteric ischemia.
Keywords
References
- 1) Abou-Ismail MY, Diamond A, Kapoor S, Arafah Y, Nayak L. The hypercoagulable state in COVID-19: incidence, pathophysiology, and management. Thrombosis Research 2020;194:101–115.
- 2) Song JC, Wang G, Zhang W, Zhang Y, Li WQ, Zhou Z, et al. Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19. Military Medical Research 2020;7:19:1.
- 3) Avila J, Long B, Holladay D, Gottlieb M. Thrombotic complications of COVID 19. The American Journal of Emergency Medicine 2021;39:213–218.
- 4) Moheb ME, Naar L, Christensen MA, Kapoen C, Maurer LR, Farhat M, et al. Gastrointestinal complications in critically ill patients with and without COVID-19. JAMA 2020;324:18:1899–1901.
- 5) Bala M, Kashuk J, Moore EE, Kluger Y, Biffl W, Gomes CA, et al. Acute mesenteric ischemia: guidelines of the World Society of Emergency Surgery. World Journal of Emergency Surgery 2017;12:38.
- 6) Heys SD, Brittenden J, Crofts TJ. Acute mesenteric ischaemia: the continuing difficulty in early diagnosis. Postgrad Med J 1993;69:48-51.
- 7) Lodigiani C, Iapichino G, Carenzo L, Cecconi M, Ferrazzi P, Sebastian T, et al. Venous and arterial thromboembolic complications in COVID-19 patients admitted to an academic hospital in Milan, Italy. Thromb Res 2020;191:9-14.
- 8) Kerawala AA, Das B, Solangi A. Mesenteric ischemia in COVID-19 patients: A review of current literature. World journal of clinical cases, 2021;9:18:4700-4708.
Details
Primary Language
English
Subjects
Health Care Administration
Journal Section
Research Article
Early Pub Date
June 30, 2023
Publication Date
June 30, 2023
Submission Date
April 21, 2023
Acceptance Date
June 25, 2023
Published in Issue
Year 2023 Volume: 45 Number: 2