The investigation of seroprevalence of Borrelia burgdorferi and Rickettsia conorii in people living in forest villages of Sinop

Turabi Güneş

doi:10.7197/cmj.vi.584608

EN

The investigation of seroprevalence of Borrelia burgdorferi and Rickettsia conorii in people living in forest villages of Sinop

Abstract

Objective: This study aimed to investigate the seroprevalence of Borrelia burgdorferi, the causative agent of Lyme disease, and Rickettsia conorii, the causative agent of Mediterranean spotted fever, in the Sinop region.

Method: In 2006 and 2007, the blood serum of 184 people, living in the villages of the central district of Sinop, was obtained and stored at 80ºC until the study. In these sera, IgG antibodies reactive to B. burgdorferi and R. conorii were investigated by ELISA method.

Results: Antibody positivity was found against B. burgdorferi in 36.41% and R. conorii in 45.10% of 184 people living in rural areas of Sinop. Reactive antibodies against B. burgdorferi were detected in 47.62% of 42 people with a history of redness and swelling at the contact site after the tick bite, and in 28.95% of 76 people without these symptoms (p= 0.043, OR=2.23). The seropositivity to R. conorii was found in 57.14% and 46.05% of persons with and without these symptoms, respectively (p= 0.363, OR= 1.56). There was a statistically significant increase in seroprevalence of both B. burgdorferi and R. conorii with increasing age (p<0.05). R. conorii and B. burgdorferi co-seroprevalence were determined in 16.85% of serum samples. Since the ELISA test results in both pathogens were not repeated with confirmation tests, these findings were considered possible.

Conclusions: The findings obtained in this study revealed that Sinop and similar ecological features should be evaluated within the endemic regions for B. burgdorferi and R. conorii. It should be paying attention that infections from both pathogens may be likely to appear at these regions.

Keywords

Borrelia burgdorferi,Rickettsia conorii,Lyme disease,Mediterranean Spotted Fever,Erythema Migrans

Supporting Institution

The Cumhuriyet University Scientific Research Projects Commission Presidentship

Project Number

SHMYO-OO5

Thanks

This study was supported by the Cumhuriyet University Scientific Research Projects Commission Presidentship (CUBAP) (SHMYO-OO5). During the investigation, I would like to thank the High Nurse Zübeyde Güneş for helping to collect blood from people, and thanks for Prof. Dr Ömer Poyraz and Prof. Dr Ahmet Alim for their contributions in ELISA and RPR testing.

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Research Article

Authors

Turabi Güneş ^*
0000-0002-8011-7844
Türkiye

Publication Date

December 31, 2019

Submission Date

June 30, 2019

Acceptance Date

December 31, 2019

Published in Issue

Year 2019 Volume: 41 Number: 4

DOI

https://doi.org/10.7197/cmj.vi.584608

IZ

https://izlik.org/JA92CZ72XF

Cite

RIS / Bibtex

AMA

1.Güneş T. The investigation of seroprevalence of Borrelia burgdorferi and Rickettsia conorii in people living in forest villages of Sinop. CMJ. 2019;41(4):676-684. doi:10.7197/cmj.vi.584608

Öz

The investigation of seroprevalence of Borrelia burgdorferi and Rickettsia conorii in people living in forest villages of Sinop

Abstract

Keywords

Supporting Institution

Project Number

Thanks

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite