Decellularization of tissues and organs

Nevra Pelin Cesur; Volkan Yalman; Nelisa Laçin Türkoğlu

doi:10.7197/cmj.vi.609592

TR EN

Decellularization of tissues and organs

Abstract

Decellularized tissues and organs have been successfully used in various tissue engineering and regenerative medicine applications. A biological scaffold obtained from the extracellular matrix can be produced by a variety of decellularization methods that effectively remove cells from the tissue to be treated. Decellularization methods is changed according to the target structure of tissues and organs. These methods can be summarized with chemically, physically, enzymatically and using Supercritical Fluid Extraction (SFE) ways. Each of these methods affects the biochemical composition in the structure of the remaining extracellular matrix (ECM), the structure of the tissue (ultrastructure), and the mechanical behavior. In this article, the most commonly used decellulization methods are introduced and their effects on biological tissue scaffold materials are discussed.

Keywords

References

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Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Review

Authors

Nevra Pelin Cesur
0000-0003-3979-6053
Türkiye

Volkan Yalman
0000-0001-8267-9712
Türkiye

Nelisa Laçin Türkoğlu ^*
0000-0003-3176-0902
Türkiye

Publication Date

July 21, 2020

Submission Date

August 22, 2019

Acceptance Date

July 6, 2020

Published in Issue

Year 2020 Volume: 42 Number: 2

DOI

https://doi.org/10.7197/cmj.vi.609592

IZ

https://izlik.org/JA32KY94SS

Cite

RIS / Bibtex

AMA

1.Cesur NP, Yalman V, Laçin Türkoğlu N. Decellularization of tissues and organs. CMJ. 2020;42(2):192-197. doi:10.7197/cmj.vi.609592

Decellularization of tissues and organs

Dokuların ve organların hücresizleştirilmesi

Öz

Anahtar Kelimeler

Decellularization of tissues and organs

Abstract

Keywords

References

Details

Primary Language

Subjects

Journal Section

Authors

Publication Date

Submission Date

Acceptance Date

Published in Issue

DOI

IZ

Cite