Abstract
Objective: Our aim is
to evaluate the analysis of perinatal characteristics of cases diagnosed with
fetal intracranial anomaly of tertiary care center over the last 10 years.
Method: A cross-sectional study of 59
pregnant women diagnosed with fetal brain anomalies between 11 and 33 weeks of
gestational age (GA). The data were
collected from the archive. After that, intracranial anomalies were divided
into subtypes and how often they are seen. Descriptive statistics of collected
variables were calculated.
Results: 59 cases were diagnosed with
an average of 19.3 ± 5.4 weeks of gestational age. Karyotype abnormality was
detected in 18.6% of cases. The most common intracranial anomalies in our study
were ventriculomegaly (35.6%), Arnold Chiari malformation (20.3%) and
encephalocele (20.3%).
Conclusions: Despite the challenges of early gestation, accuracy in diagnosing and counseling
to family for fetal brain anomalies before 24 weeks'
GA was high. A multidisciplinary approach involving pediatrics,
genetics, and neurosurgery, radiology, and obstetrics and gynecology
departments is crucial for counseling on perinatal diagnosis.
References
- 1. Köşüş A, Köşüş N, Usluoğulları B, Duran M, Turhan NÖ, Tekşam M. Fetal magnetic resonance imaging in obstetric practice. J Turk Ger Gynecol Assoc 2011; 12: 39-46.
- 2. Garcia-Flores J, Recio M, Uriel M, Cañamares M, Cruceyra M, Tamarit I, Carrascoso J, Espada M, Sáinz de la Cuesta R. Fetal magnetic resonance imaging and neurosonography in congenital neurological anomalies: supplementary diagnostic and postnatal prognostic value. J Matern Fetal Neonatal Med 2013; 26: 1517-23.
- 3. Trudell AS, Odibo AO. Diagnosis of spina bifida on ultrasound: always termination? Best Pract Res Clin Obstet Gynaecol 2014; 28: 367-77.
- 4. Kahn L, Mbabuike N, Valle-Giler EP, Garces J, Moore RC, Hilaire HS, Bui CJ. Fetal surgery: the ochsner experience with in utero spina bifida repair. Ochsner J 2014; 14: 112-8.
- 5. Balakumar K. Antenatal ultrasound screening for anomalies among singletons- results of a prospective study. Calicut Medical Journal 2004; 2: 1-10
- 6. Davies V, Gledhill J, McFadyen A, Whitlow B, Economides D. Psychological outcome in women undergoing termination of pregnancy for ultrasound-detected fetal anomaly in the first and second trimesters: a pilot study. Ultrasound Obstet Gynecol 2005; 25: 389-92.
- 7. lknur Gümüş, Atalay Ekin, Ceren Gölbaşı, Ezgi Hürcan, Cüneyt Eftal Taner. Evaluating 101 cases with the anomaly of fetal central nervous system. Perinatal Journal 2016; 24: 136-141
- 8. Simon EM, Goldstein RB, Coakley FV, Filly RA, Broderick KC, Musci TJ, Barkovich AJ. Fast MR imaging of fetal CNS anomalies in utero. AJNR Am J Neuroradiol 2000; 21: 1688-98.
- 9. Emine Aydın, Mert Turgal, Sema Can, Özgür Özyüncü.Posterior fossa anomalies: related anomalies and the methods of pregnancy termination. Perinatal Journal 2016; 24: 89-95
- 10. Griffiths PD, Bradburn M, Campbell MJ, Connolly DJA, Cooper CL, Jarvis D, Kilby MD, Mason G, Mooney C, Robson SC, Wailoo A; MERIDIAN Collaborative Group. Change in diagnostic confidence brought about by using in utero MRI for fetal structural brain pathology: analysis of the MERIDIAN cohort. Clin Radiol 2017; 72: 451-7.
- 11. Molina-Giraldo S, Alfonso-Ospina L, Parra-Meza C, Lancheros-García EA, Rojas-Arias JL, Acuña-Osorio E. Prevalence in birth defects diagnosed by ultrasound: three years experience in university maternal fetal medicine unit. Ginecol Obstet Mex 2015; 83: 680-9.
- 12. Mansouri HA. Central nervous system anomalies diagnosed antenatally and post-delivery management. Saudi Med J 2010; 31: 257-61.
- 13. Sefidbakht S, Dehghani S, Safari M, Vafaei H, Kasraeian M. Fetal Central Nervous System Anomalies Detected by Magnetic Resonance Imaging: A Two-Year Experience. Iran J Pediatr 2016; 26: e4589.
- 14. Ghavami M, Abedinzadeh R. Prevalence of perinatal central nervous system anomalies in East Azarbaijan-Iran. Iran J Radiol 2011; 8: 79-81.
- 15. Wald M, Lawrenz K, Deutinger J, Weninger M. Verification of anomalies of the central nervous system detected by prenatal ultrasound. Ultraschall Med 2004; 25: 214-7.
Abstract
Amaç: Amacımız, son 10 yıl içerisinde, üçüncü basamakta
fetal intrakranyal anomali tanısı konan olguların perinatal özelliklerinin
değerlendirilmesidir.
Yöntem: Çalışma, kesitsel olarak gebelik haftası 11 ve 33
hafta arasında olan fetal beyin anomalileri saptanan 59 gebeden oluşmakta idi.
Veriler arşivden toplandı. Bundan sonra intrakranyal anomaliler alt tiplere
ayrılarak görülme sıklıkları belirlendi. Toplanan değişkenlerin tanımlayıcı
istatistikleri hesaplandı.
Bulgular: 59 olgunun, gebelik haftasının ortalama 19.3 ± 5.4
hafta olduğu tespit edildi. Olguların% 18.sında karyotip anormalliği tespit
edildi. Çalışmamızda en sık görülen intrakranyal anomaliler ventrikülomegali (%
35.6), Arnold chiari malformasyonu (% 20.3) ve ensefalosel (% 20.3) idi.
Sonuç: Erken gebelik haftasında tanının zorluklarına rağmen,
gestasyonel yaşın 24 haftasından önce fetal beyin anomalilerine doğru tanı
konma oranı yüksekti. Kadın Hastalıkları ve doğum, pediatri, genetik,
nöroşirürji ve radyoloji bölümlerini içeren multidisipliner bir yaklaşım,
perinatal teşhis için çok önemlidir.
Keywords
References
- 1. Köşüş A, Köşüş N, Usluoğulları B, Duran M, Turhan NÖ, Tekşam M. Fetal magnetic resonance imaging in obstetric practice. J Turk Ger Gynecol Assoc 2011; 12: 39-46.
- 2. Garcia-Flores J, Recio M, Uriel M, Cañamares M, Cruceyra M, Tamarit I, Carrascoso J, Espada M, Sáinz de la Cuesta R. Fetal magnetic resonance imaging and neurosonography in congenital neurological anomalies: supplementary diagnostic and postnatal prognostic value. J Matern Fetal Neonatal Med 2013; 26: 1517-23.
- 3. Trudell AS, Odibo AO. Diagnosis of spina bifida on ultrasound: always termination? Best Pract Res Clin Obstet Gynaecol 2014; 28: 367-77.
- 4. Kahn L, Mbabuike N, Valle-Giler EP, Garces J, Moore RC, Hilaire HS, Bui CJ. Fetal surgery: the ochsner experience with in utero spina bifida repair. Ochsner J 2014; 14: 112-8.
- 5. Balakumar K. Antenatal ultrasound screening for anomalies among singletons- results of a prospective study. Calicut Medical Journal 2004; 2: 1-10
- 6. Davies V, Gledhill J, McFadyen A, Whitlow B, Economides D. Psychological outcome in women undergoing termination of pregnancy for ultrasound-detected fetal anomaly in the first and second trimesters: a pilot study. Ultrasound Obstet Gynecol 2005; 25: 389-92.
- 7. lknur Gümüş, Atalay Ekin, Ceren Gölbaşı, Ezgi Hürcan, Cüneyt Eftal Taner. Evaluating 101 cases with the anomaly of fetal central nervous system. Perinatal Journal 2016; 24: 136-141
- 8. Simon EM, Goldstein RB, Coakley FV, Filly RA, Broderick KC, Musci TJ, Barkovich AJ. Fast MR imaging of fetal CNS anomalies in utero. AJNR Am J Neuroradiol 2000; 21: 1688-98.
- 9. Emine Aydın, Mert Turgal, Sema Can, Özgür Özyüncü.Posterior fossa anomalies: related anomalies and the methods of pregnancy termination. Perinatal Journal 2016; 24: 89-95
- 10. Griffiths PD, Bradburn M, Campbell MJ, Connolly DJA, Cooper CL, Jarvis D, Kilby MD, Mason G, Mooney C, Robson SC, Wailoo A; MERIDIAN Collaborative Group. Change in diagnostic confidence brought about by using in utero MRI for fetal structural brain pathology: analysis of the MERIDIAN cohort. Clin Radiol 2017; 72: 451-7.
- 11. Molina-Giraldo S, Alfonso-Ospina L, Parra-Meza C, Lancheros-García EA, Rojas-Arias JL, Acuña-Osorio E. Prevalence in birth defects diagnosed by ultrasound: three years experience in university maternal fetal medicine unit. Ginecol Obstet Mex 2015; 83: 680-9.
- 12. Mansouri HA. Central nervous system anomalies diagnosed antenatally and post-delivery management. Saudi Med J 2010; 31: 257-61.
- 13. Sefidbakht S, Dehghani S, Safari M, Vafaei H, Kasraeian M. Fetal Central Nervous System Anomalies Detected by Magnetic Resonance Imaging: A Two-Year Experience. Iran J Pediatr 2016; 26: e4589.
- 14. Ghavami M, Abedinzadeh R. Prevalence of perinatal central nervous system anomalies in East Azarbaijan-Iran. Iran J Radiol 2011; 8: 79-81.
- 15. Wald M, Lawrenz K, Deutinger J, Weninger M. Verification of anomalies of the central nervous system detected by prenatal ultrasound. Ultraschall Med 2004; 25: 214-7.
Details
| Subjects | Health Care Administration |
|---|---|
| Journal Section | Medical Science Research Articles |
| Authors | |
| Publication Date | September 19, 2017 |
| Acceptance Date | June 20, 2017 |
| Published in Issue | Year 2017 |