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Evaluation of cornea with specular microscopy in patients with ocular rozacea

Year 2021, , 90 - 96, 31.03.2021
https://doi.org/10.7197/cmj.827876

Abstract

Objective: To investigate changes in corneal endothelial cell density, corneal morphology and central corneal thickness in patients with ocular rosacea.
Method: 60 eyes of 30 ocular rosacea patients and 60 eyes of 30 control group with similar demographic characteristics were included in the study. Detailed ophthalmological examination was performed in all individuals participating in the study. The eyes of all participants were evaluated by specular microscopy, schirmer 1 test, tear break-up time test (TBUT). Additionally, via specular microscopy the following parameters were assessed: endothelial cell density (ECD), mean cell area (ACA), minimum cell area (CAmin), maximum cell area (CA max), cell area standard deviation (SD), coefficient of variation in the cell area (CV), hexogonal cell ratio (HEX), central corneal thickness (CCT) numerical (NUM).
Results: Although none of the differences are statistically significant, patients with ocular rosacea have lower ACA, CA min, CA max, HEX, CCT and NUM values (p = 0,169, p = 0,897, p = 0,694, p = 0,649, p = 0,164 and p = 0,070, respectively), and higher CD, SD and CV values (p = 0.509, p = 0.437, p = 0.165, respectively). In ocular rosacea patients, there was no significant correlation was found the values of mean Schirmer test between CV, HEX, ECD, CT (p = 0.394, p = 0.906, p = 0.222, p = 0.208, respectively). Additionally, no significant correlation was found between tear break-up time and CV, HEX, ECD, CCT (p = 0.079, p = 0.227, p = 0.621, p = 0.712, respectively).
Conclusions: Our finding show that, despite the presence of some observable differences, corneal endothelial functions are similar to control group in patients with ocular rosacea.

Supporting Institution

Adıyaman University Faculty of Medicine

Project Number

2017/8-2

References

  • 1 Wilkin J, Dahl M, Detmar M. Standard classification of rosacea: report of the national rosacea society expert committee on the classification and staging of rosacea. J Am Acad Dermatol 2002; 46:584–587.
Year 2021, , 90 - 96, 31.03.2021
https://doi.org/10.7197/cmj.827876

Abstract

Project Number

2017/8-2

References

  • 1 Wilkin J, Dahl M, Detmar M. Standard classification of rosacea: report of the national rosacea society expert committee on the classification and staging of rosacea. J Am Acad Dermatol 2002; 46:584–587.
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Details

Primary Language English
Subjects Health Care Administration
Journal Section Surgical Science Research Articles
Authors

Ali Hakim Reyhan 0000-0001-8402-0954

Şerife Çınar 0000-0001-8377-0753

Birgül Özkesici 0000-0003-3121-5816

Ayşe Sevgi Karadağ 0000-0002-7662-6531

Project Number 2017/8-2
Publication Date March 31, 2021
Acceptance Date March 29, 2021
Published in Issue Year 2021

Cite

AMA Reyhan AH, Çınar Ş, Özkesici B, Karadağ AS. Evaluation of cornea with specular microscopy in patients with ocular rozacea. CMJ. March 2021;43(1):90-96. doi:10.7197/cmj.827876