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Year 2016, Volume: 38 Issue: 4, 223 - 230, 25.11.2016
https://doi.org/10.7197/cmj.v38i4.5000207924

Abstract

HISTOLOGICAL APPROACHES TO DETERMINATION OF STEM CELLS IN NEURAL TUBE DEFECTS WHICH ARE CREATED EXPERIMENTALLY

Year 2016, Volume: 38 Issue: 4, 223 - 230, 25.11.2016
https://doi.org/10.7197/cmj.v38i4.5000207924

Abstract

Stem cells are cells that are started to be seen in the early stages of development and they have important roles in development of both neural system and other systems. Anomalies that occur with the neural tubes inability to close are known as neural tube defects. Neural tube defects can be due to malfunction of gene area and many mechanisms since the moment neural tube starts to develop. The incidence of neural tube defect is very high in our country and in the world. Therefore, to understand the neural tube defects in the people, necessary data is usually collected by giving teratogen agent to subject animals. With this compilation, experimental neural tube defects have been formed and immunohistochemistry and     immunofluorescent studies of some stem cells that are thought to have role in the formation of defect are compiled. From this point of view, it is aimed to determine the distributions of neural tube in rhe processes of normal development and defect formation, to understand the reproduction and alteration mechanisms of stem cells, and        concomitantly to reveal the defect pathogenesis.

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Details

Subjects Health Care Administration
Journal Section Reviews
Authors

Zeynep Deniz Şahin İnan

Serpil Ünver Saraydın

Publication Date November 25, 2016
Published in Issue Year 2016Volume: 38 Issue: 4

Cite

AMA Şahin İnan ZD, Ünver Saraydın S. HISTOLOGICAL APPROACHES TO DETERMINATION OF STEM CELLS IN NEURAL TUBE DEFECTS WHICH ARE CREATED EXPERIMENTALLY. CMJ. November 2016;38(4):223-230. doi:10.7197/cmj.v38i4.5000207924