Abstract
References
- Bejjani GK. Definition of the adult Chiari malformation: a brief historical overview. Neurosurg Focus 200; 11: E1.
- Deniz FE, Öksüz E. Spontaneous syringomyelia resolution at an adult Chiari type 1 malformation. Turk Neurosurg 2009; 19: 96-8.
- Eser O, Haktanır A, Boyacı MG, Doğan FA, Karavelioğlu E. Korpus kallozumun morfometrik ölçümleri. Türk Nöroşirürji Dergisi 2011; 21: 14-7.
- Erdoğan N, Ulger H, Tuna I, Okur A. A novel index to estimate the corpus callosum morphometry in adults: callosal/supratentorial-supracallosal area ratio. Diagn Interv Radiol 2005; 11: 179-81.
- Venkatasubramanian G, Anthony G, Reddy US, Reddy VV, Jayakumar PN, Benegal V. Corpus callosum abnormalities associated with greater externalizing behaviors in subjects at high risk for alcohol dependence. Psychiatry Res 2007; 156: 209-15.
- Hwang SJ, Park C, Hong HN, Ryu JY, Rhyu IJ, Park IS. Effects of age and gender on spatial orientation of human corpus callosum in healthy Koreans. Animal Cells and Systems 2011; 15: 274-8.
- Uchino A, Kato A, Yuzuriha T, Takashima Y, Kudo S. Cranial MR imaging of sequelae of prefrontal lobotomy. AJNR Am J Neuroradiol 2001; 22: 301-4.
- Meguro K, Constans JM, Courtheoux P, Theron J, Viader F, Yamadori A. Atrophy of the corpus callosum correlates with white matter lesions in patients with cerebral ischaemia. Neuroradiology 2000; 42: 413-9.
- DeLacoste-Utamsing C, Holloway RL. Sexual dimorphism in the human corpus callosum. Science 1982; 216: 1431-2.
- Hwang SJ, Ji EK, Lee EK, Kim YM, Shin DY, Cheon YH, Rhyu IJ. Gender differences in the corpus callosum of neonates. Neuroreport 2004; 15: 1029-32.
- Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain 1989; 112:799-835.
- Byne W, Bleier R, Houston L. Variations in human corpus callosum do not predict gender: a study using magnetic resonance imaging. Behav Neurosci 1988; 102: 222-7.
- Allen LS, Richey MF, Chai YM, Gorski RA. Sex differences in the corpus callosum of the living human being. J Neurosci 1991; 11: 933-42.
- Sullivan EV, Pfefferbaum A, Adalsteinsson E, Swan GE, Carmelli D. Differential rates of regional brain change in callosal and ventricular size: a 4-year longitudinal MRI study of elderly men. Cereb Cortex 2002; 12: 438-45.
- Suganthy J, Raghuram L, Antonisamy B, Vettivel S, Madhavi C, Koshi R. Gender- and age-related differences in the morphology of the corpus callosum. Clin Anat 2003; 16: 396-403.
- Serpa MH, Schaufelberger MS, Rosa PG, Duran FL, Santos LC, Muray RM, Scazufca M, Menezes PR, Busatto GF. Corpus callosum volumes in recent-onset schizophrenia are correlated to positive symptom severity after 1 year of follow- up. Schizophr Res 2012; 137: 258-9.
- Luders E, Rex DE, Narr KL, Woods RP, Jancke L, Thompson PM, Mazziotta JC, Toga AW. Relationships between sulcal asymmetries and corpus callosum size: Gender and handedness effects. Cereb Cortex 2003; 13: 1084-93.
- Bishop KM, Wahlsten D. Sex differences in the human corpus callosum: myth or reality? Neurosci Biobehav Rev 1997; 21: 581-601.
- Oka S, Miyamoto O, Janjua NA, Honjo-Fujiwara N, Ohkawa M, Nagao S, Kondo H, Minami T, Toyoshima T, Itano T. Re-evaluation of sexual dimorphism in human corpus callosum. Neuroreport 1999; 10: 937-40.
- Takeda S, Hirashima Y, Ikeda H, Yamamoto H, Sugino M, Endo S. Determination of indices of the corpus callosum associated with normal aging in Japanese individuals. Neuroradiology 2003; 45: 513-8.
- Furtado SV, Reddy K, Hegde AS. Posterior fossa morphometry in symptomatic pediatric and adult Chiari I malformation. J Clin Neurosci 2009; 16: 1449-54.
- Vurdem ÜE, Acer N, Ertekin T, Savranlar A, Inci MF. Analysis of the volumes of the posterior cranial fossa, cerebellum, and herniated tonsils using the stereological methods in patients with Chiari type I malformation. ScientificWorldJournal 2012; 2012: 616934.
- Nishikawa M, Sakamoto H, Hakuba A, Nakanishi N, Inoue Y. hdshdd Pathogenesis of Chiari malformation: a morphometric study of the posterior cranial fossa. J Neurosurg 1997; 86: 40-7.
Chiari tip I malformasyonlu hastalarda korpus kallozumun morfometrik ölçümlerinin ve uzaysal oryantasyonunun değerlendirilmesi
Abstract
Özet
Amaç. Bu çalışmada, Chiari tip I malformasyonlu hastalarda korpus kallozumun morfometrik ölçümleri ve birtakım açı ölçümleri ile tespit edilen uzaysal oryentasyonunu normal populasyona göre değerlendirmek amaçlanmıştır. Yöntem. 3-65 yaş arası 28 Chiari tip I malformasyonlu hasta (14 kadın, 14 erkek) ve 41 sağlıklı olgunun, T1 veya T2 ağırlıklı orta sagital kesitli MR görüntülerinde korpus kallozumun uzunluk, yükseklik, tepe açısı ve uzaysal oryentasyonunu belirleyen 4 farklı açı (A, B, C, D açıları) ölçümü yapıldı. Ölçümler arası farkı belirlemek için istatistiksel olarak Independent-T testi kullanıldı. Korelasyon için Pearson korelasyon testi kullanıldı. Bulgular. Her iki grup karşılaştırıldığında oryentasyon açılarından B ve D açılarında anlamlı bir fark olduğu bulundu (p<0,05). A ve C açılarında, korpus kallozumun uzunluk, yükseklik ve santral açı ölçümlerinde ise istatistiksel olarak anlamlı bir fark bulunmadı (p>0,05).Yaş ile korpus kallozumun uzunluğu ve A açısı arasında pozitif korelasyon saptandı. (sırasıyla r: 0,446 p: 0,043, r: 0,494 p: 0,023). Cinsiyet ile morfometrik ölçümler ve açılar arasında anlamlı korelasyon saptanmadı. Sonuç. Korpus kallozumun uzaysal oryentasyonu Chiari tip I malformasyonlu olgularda normal populasyona göre farklılık göstermektedir. Bu sonuçlar, korpus kallozum çalışmalarında uzaysal oryentasyonun önemli bir faktör olabileceğini göstermekle birlikte daha geniş serilere ihtiyaç vardır.
Anahtar sözcükler: Chiari tip I malformasyonu, korpus kallozum, morfometrik ölçümler, uzaysal oryantasyon
Abstract
Aim. This study aimed to determine the morphometric measurement and spatial orientation of corpus callosum in patients with Chiari type I malformation. Methods. In 28 patients with Chiari type I malformation (14 women and 14 men) and 41 healthy individuals between the ages of 3-65, length and height of corpus callosum as well as the central angle and four angles (A, B, C, D angles) to understand the spatial characteristics of the callosum were measured in T1 or T2 weighted mid-sagittal MR images. Independent-T test was used to determine the statistical differences between the measurements. Moreover Pearson's coefficient of correlation was used to determine the correlations. Results. B and D angles of corpus callosum compared between the groups, had a significant difference (p<0.001). There was no statistical difference between the length and height of corpus callosum, as well as the central angle and other two angles (A and C) for spatial characteristics of the corpus callosum (p>0.05). There was a positive correlation between the age and length of corpus callosum and A angle (r: 0.446 p: 0.043, r: 0.494 p: 0.023, respectively). There was no correlation between gender and morphometric measurements. Conclusion. These results confirm that the spatial orientation of corpus callosum is different from the normal population in cases with Chiari Type I malformation. These results suggest that spatial orientation could be an important factor in studies of the corpus callosum, however, further studies are required with larger sample size.
Keywords: Chiari type I malformation, Corpus callosum, morphometric measurements, spatial orientation
References
- Bejjani GK. Definition of the adult Chiari malformation: a brief historical overview. Neurosurg Focus 200; 11: E1.
- Deniz FE, Öksüz E. Spontaneous syringomyelia resolution at an adult Chiari type 1 malformation. Turk Neurosurg 2009; 19: 96-8.
- Eser O, Haktanır A, Boyacı MG, Doğan FA, Karavelioğlu E. Korpus kallozumun morfometrik ölçümleri. Türk Nöroşirürji Dergisi 2011; 21: 14-7.
- Erdoğan N, Ulger H, Tuna I, Okur A. A novel index to estimate the corpus callosum morphometry in adults: callosal/supratentorial-supracallosal area ratio. Diagn Interv Radiol 2005; 11: 179-81.
- Venkatasubramanian G, Anthony G, Reddy US, Reddy VV, Jayakumar PN, Benegal V. Corpus callosum abnormalities associated with greater externalizing behaviors in subjects at high risk for alcohol dependence. Psychiatry Res 2007; 156: 209-15.
- Hwang SJ, Park C, Hong HN, Ryu JY, Rhyu IJ, Park IS. Effects of age and gender on spatial orientation of human corpus callosum in healthy Koreans. Animal Cells and Systems 2011; 15: 274-8.
- Uchino A, Kato A, Yuzuriha T, Takashima Y, Kudo S. Cranial MR imaging of sequelae of prefrontal lobotomy. AJNR Am J Neuroradiol 2001; 22: 301-4.
- Meguro K, Constans JM, Courtheoux P, Theron J, Viader F, Yamadori A. Atrophy of the corpus callosum correlates with white matter lesions in patients with cerebral ischaemia. Neuroradiology 2000; 42: 413-9.
- DeLacoste-Utamsing C, Holloway RL. Sexual dimorphism in the human corpus callosum. Science 1982; 216: 1431-2.
- Hwang SJ, Ji EK, Lee EK, Kim YM, Shin DY, Cheon YH, Rhyu IJ. Gender differences in the corpus callosum of neonates. Neuroreport 2004; 15: 1029-32.
- Witelson SF. Hand and sex differences in the isthmus and genu of the human corpus callosum. A postmortem morphological study. Brain 1989; 112:799-835.
- Byne W, Bleier R, Houston L. Variations in human corpus callosum do not predict gender: a study using magnetic resonance imaging. Behav Neurosci 1988; 102: 222-7.
- Allen LS, Richey MF, Chai YM, Gorski RA. Sex differences in the corpus callosum of the living human being. J Neurosci 1991; 11: 933-42.
- Sullivan EV, Pfefferbaum A, Adalsteinsson E, Swan GE, Carmelli D. Differential rates of regional brain change in callosal and ventricular size: a 4-year longitudinal MRI study of elderly men. Cereb Cortex 2002; 12: 438-45.
- Suganthy J, Raghuram L, Antonisamy B, Vettivel S, Madhavi C, Koshi R. Gender- and age-related differences in the morphology of the corpus callosum. Clin Anat 2003; 16: 396-403.
- Serpa MH, Schaufelberger MS, Rosa PG, Duran FL, Santos LC, Muray RM, Scazufca M, Menezes PR, Busatto GF. Corpus callosum volumes in recent-onset schizophrenia are correlated to positive symptom severity after 1 year of follow- up. Schizophr Res 2012; 137: 258-9.
- Luders E, Rex DE, Narr KL, Woods RP, Jancke L, Thompson PM, Mazziotta JC, Toga AW. Relationships between sulcal asymmetries and corpus callosum size: Gender and handedness effects. Cereb Cortex 2003; 13: 1084-93.
- Bishop KM, Wahlsten D. Sex differences in the human corpus callosum: myth or reality? Neurosci Biobehav Rev 1997; 21: 581-601.
- Oka S, Miyamoto O, Janjua NA, Honjo-Fujiwara N, Ohkawa M, Nagao S, Kondo H, Minami T, Toyoshima T, Itano T. Re-evaluation of sexual dimorphism in human corpus callosum. Neuroreport 1999; 10: 937-40.
- Takeda S, Hirashima Y, Ikeda H, Yamamoto H, Sugino M, Endo S. Determination of indices of the corpus callosum associated with normal aging in Japanese individuals. Neuroradiology 2003; 45: 513-8.
- Furtado SV, Reddy K, Hegde AS. Posterior fossa morphometry in symptomatic pediatric and adult Chiari I malformation. J Clin Neurosci 2009; 16: 1449-54.
- Vurdem ÜE, Acer N, Ertekin T, Savranlar A, Inci MF. Analysis of the volumes of the posterior cranial fossa, cerebellum, and herniated tonsils using the stereological methods in patients with Chiari type I malformation. ScientificWorldJournal 2012; 2012: 616934.
- Nishikawa M, Sakamoto H, Hakuba A, Nakanishi N, Inoue Y. hdshdd Pathogenesis of Chiari malformation: a morphometric study of the posterior cranial fossa. J Neurosurg 1997; 86: 40-7.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Medical Science Research Articles |
| Authors | |
| Publication Date | October 1, 2012 |
| Published in Issue | Year 2012Volume: 34 Issue: 4 |