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The effect of levosimendan in a patients with postinfarction ventricular septal defect

Year 2015, Volume: 37 Issue: 1, 58 - 60, 27.03.2015
https://doi.org/10.7197/cmj.v37i1.5000075349

Abstract

SUMMARY

This paper reports the clinic course of a patient with postinfarction ventricular septal defect (VSD). At the period to surgery, the patient received levosimendan for cardio-protection. During the levosimendan infusion, the hemodynamics of the patient worsened. The impairment of hemodynamics and mortality of the patient might be responded to the increase of the amount of left to right shunt, which had possibly occurred due to levosimendan treatment.

Keywords: Levosimendan, acute myocardial infarction, ventricular septal defect, shunt

ÖZET

Bu yazı, akut miyokard infarktüsü sonrası ventriküler septal defekt (VSD) gelişen birhastanın klinik seyrini içermektedir. Cerrahiyi bekleme sürecinde, hastaya kardiyak koruma amacıyla levosimendan infüzyonu başlandı. İnfüzyon esnasında hastanın hemodinamisi kötüleşti. Hemodinamideki bozulmanın, levosimendan tedavisine sekonder soldan sağa şant miktarının artışına bağlı olabileceği düşünüldü.

Anahtar sözcükler: Levosimendan, akut miyokard infarktüsü, ventriküler septal defekt, şant

References

  • Pohjola-Sintonen S, Muller JE, Stone PH. Ventricular septal and free wall rupture complicating acute myocardial infarction: Expe- rience in the Multicenter Investiga- tion of Limitation of Infarct Size. Am Heart J 1989; 117: 809-18.
  • Van de Werf F, Bax J, Betriu A. Management of acute myocardial infarction in patients presenting with persistent ST-segment eleva- tion: The Task Force on the Man- agement of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J 2008; 29: 2909-45.
  • Menon V, Webb JG, Hillis LD. Outcome and profile of ventricular septal rupture with cardiogenic shock after myocardial infarction: A report from the SHOCK Trial Registry. SHould we emergently revascularize Occluded Coronaries in cardiogenic shocK? J Am Coll Cardiol 2000; 36: 1110-6.
  • Maltais S, Ibrahim R, Basmadjian AJ. Postinfarction ventricular sep- tal defects: Towards a new treat- ment algorithm? Ann Thorac Surg 2009; 87: 687-92.
  • Landoni G, Mizzi A, Biondi- Zoccai G. Reducing mortality in cardiac mendan: A meta-analysis of ran- domized controlled trials. J Cardi- othorac Vasc Anesth 2010; 24: 51- 7. levosi
  • Moore CA, Nygaard TW, Kaiser DL. Postinfarction ventricular sep- tal rupture: the importance of loca- tion of infarction and right ven- tricular function in determining survival. Circulation 1986; 74: 45- 55.
  • Mebazaa A, Nieminen MS, Packer M. Levosimendan vs dobutamine for patients with acute decompen- sated heart failure: The SURVIVE Randomized Trial. JAMA 2007; 297: 1883-91.
  • Boucek MM, Chang R, Synhorst DP. Hemodynamic consequences of inotropic support with digoxin or amrinone in lambs with ventric- ular septal defect. Pediatr Res 1985; 19: 887-91.
  • Momoi N, Sato M, Sato K. Hemo- dynamic effects III inhibitor in pa- tients with a large ventricular left- to-right shunt. Jpn Circ J 2000; 64: 249-53.
  • Yilmaz MB, Yontar C, Erdem A. Comparative effects of levosi- mendan and dobutamine on right ventricular function in patients with biventricular heart failure. Heart Vessels 2009; 24: 16-21.
  • Lowe JE, Gall SA Jr. As originally published in 1989: Correlates of survival with postinfarction ven- tricular septal defect. Ann Thorac Surg 1997; 63: 1508-9.

İnfarktüs sonrası ventriküler septal defektli hastada Levosimendan’ın etkisi

Year 2015, Volume: 37 Issue: 1, 58 - 60, 27.03.2015
https://doi.org/10.7197/cmj.v37i1.5000075349

Abstract

Bu yazı, akut miyokard infarktüsü sonrası ventriküler septal defekt (VSD) gelişen birhastanın klinik seyrini içermektedir. Cerrahiyi bekleme sürecinde, hastaya kardiyak koruma amacıyla levosimendan infüzyonu başlandı. İnfüzyon esnasında hastanın hemodinamisi kötüleşti. Hemodinamideki bozulmanın, levosimendan tedavisine sekonder soldan sağa şant miktarının artışına bağlı olabileceği düşünüldü

References

  • Pohjola-Sintonen S, Muller JE, Stone PH. Ventricular septal and free wall rupture complicating acute myocardial infarction: Expe- rience in the Multicenter Investiga- tion of Limitation of Infarct Size. Am Heart J 1989; 117: 809-18.
  • Van de Werf F, Bax J, Betriu A. Management of acute myocardial infarction in patients presenting with persistent ST-segment eleva- tion: The Task Force on the Man- agement of ST-Segment Elevation Acute Myocardial Infarction of the European Society of Cardiology. Eur Heart J 2008; 29: 2909-45.
  • Menon V, Webb JG, Hillis LD. Outcome and profile of ventricular septal rupture with cardiogenic shock after myocardial infarction: A report from the SHOCK Trial Registry. SHould we emergently revascularize Occluded Coronaries in cardiogenic shocK? J Am Coll Cardiol 2000; 36: 1110-6.
  • Maltais S, Ibrahim R, Basmadjian AJ. Postinfarction ventricular sep- tal defects: Towards a new treat- ment algorithm? Ann Thorac Surg 2009; 87: 687-92.
  • Landoni G, Mizzi A, Biondi- Zoccai G. Reducing mortality in cardiac mendan: A meta-analysis of ran- domized controlled trials. J Cardi- othorac Vasc Anesth 2010; 24: 51- 7. levosi
  • Moore CA, Nygaard TW, Kaiser DL. Postinfarction ventricular sep- tal rupture: the importance of loca- tion of infarction and right ven- tricular function in determining survival. Circulation 1986; 74: 45- 55.
  • Mebazaa A, Nieminen MS, Packer M. Levosimendan vs dobutamine for patients with acute decompen- sated heart failure: The SURVIVE Randomized Trial. JAMA 2007; 297: 1883-91.
  • Boucek MM, Chang R, Synhorst DP. Hemodynamic consequences of inotropic support with digoxin or amrinone in lambs with ventric- ular septal defect. Pediatr Res 1985; 19: 887-91.
  • Momoi N, Sato M, Sato K. Hemo- dynamic effects III inhibitor in pa- tients with a large ventricular left- to-right shunt. Jpn Circ J 2000; 64: 249-53.
  • Yilmaz MB, Yontar C, Erdem A. Comparative effects of levosi- mendan and dobutamine on right ventricular function in patients with biventricular heart failure. Heart Vessels 2009; 24: 16-21.
  • Lowe JE, Gall SA Jr. As originally published in 1989: Correlates of survival with postinfarction ven- tricular septal defect. Ann Thorac Surg 1997; 63: 1508-9.
There are 11 citations in total.

Details

Primary Language English
Journal Section Case Reports
Authors

Hasan Yücel

Ali Zorlu

Hakkı Kaya

İbrahim Gül

Publication Date March 27, 2015
Published in Issue Year 2015Volume: 37 Issue: 1

Cite

AMA Yücel H, Zorlu A, Kaya H, Gül İ. The effect of levosimendan in a patients with postinfarction ventricular septal defect. CMJ. March 2015;37(1):58-60. doi:10.7197/cmj.v37i1.5000075349