Research Article
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Year 2019, Volume: 41 Issue: 3, 620 - 625, 30.09.2019
https://doi.org/10.7197/cmj.vi.475431

Abstract

References

  • Referances1. Burrows RF, Kelton JG. Fetal thrombocytopenia and its relation to maternal thrombocytopenia. N Engl J Med. 1993;329(20):1463-6.
  • Referances2. Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010;115(2):168-86.
  • Referances3. Gernsheimer T, James AH, Stasi R. How I treat thrombocytopenia in pregnancy. Blood. 2013;121(1):38-47.
  • Referances4. Boehlen F, Hohlfeld P, Extermann P, Perneger TV, de Moerloose P. Platelet count at term pregnancy: a reappraisal of the threshold. Obstetrics and gynecology. 2000;95(1):29-33.
  • Referances5. Sainio S, Kekomaki R, Riikonen S, Teramo K. Maternal thrombocytopenia at term: a population-based study. Acta obstetricia et gynecologica Scandinavica. 2000;79(9):744-9.
  • Referances6. Ruggeri M, Schiavotto C, Castaman G, Tosetto A, Rodeghiero F. Gestational thrombocytopenia: a prospective study. Haematologica. 1997;82(3):341-2.
  • Referances7. Wang X, Xu Y, Luo W, Feng H, Luo Y, Wang Y, et al. Thrombocytopenia in pregnancy with different diagnoses: Differential clinical features, treatments, and outcomes. Medicine. 2017;96(29):e7561.
  • Referances8. American College of O, Gynecologists' Committee on Practice B-O. Practice Bulletin No. 166: Thrombocytopenia in Pregnancy. Obstetrics and gynecology. 2016;128(3):e43-53.
  • Referances9. Sahin E, Madendag Y, Tayyar AT, Sahin ME, Col Madendag I, Acmaz G, et al. Perinatal outcomes in uncomplicated late preterm pregnancies with borderline oligohydramnios. J Matern Fetal Neonatal Med. 2017:1-4.
  • Referances10. Lin YH, Lo LM, Hsieh CC, Chiu TH, Hsieh TT, Hung TH. Perinatal outcome in normal pregnant women with incidental thrombocytopenia at delivery. Taiwan J Obstet Gynecol. 2013;52(3):347-50.
  • Referances11. Levy JA, Murphy LD. Thrombocytopenia in pregnancy. The Journal of the American Board of Family Practice. 2002;15(4):290-7.
  • Referances 12. http://www.tuik.gov.tr/PreHaberBultenleri.do?id=27588

Effect of gestational thrombocytopenia on negative fetal and maternal outcomes in low-risk pregnancies

Year 2019, Volume: 41 Issue: 3, 620 - 625, 30.09.2019
https://doi.org/10.7197/cmj.vi.475431

Abstract

Objective: Thrombocytopenia,
expressed as platelet counts lower than 150 × 109 /L, is a common
hematological anomaly seen in 6.6% of the pregnancies. Incidental
thrombocytopenia of the pregnancy, commonly referred
to as gestational thrombocytopenia, accounts for 70%–80% of cases.

This study aimed
to elucidate the effect of gestational thrombocytopenia on negative fetal and
maternal results in low-risk pregnancies.

Method: The
patients were divided into two groups. The control group (n = 240) consisted of healthy pregnant women with normal platelet
count, and the study group (n = 80) consisted of pregnant women with
gestational thrombocytopenia.

Results: Maternal age,
pre-pregnancy body mass indexes, parity, and previous cesarean history rates
were similar in both groups. Gestational age during delivery, fetal weight, delivery
induction, amniotic fluid stained with meconium, hyperbilirubinemia, admission
to neonatal
intensive care unit, transient
tachypnea of the newborn
, respiratory distress syndrome, hypoxic–ischemic encephalopathy, necrotizing
enterocolitis, intraventricular hemorrhage, and 5-min Apgar scores of <7 were not different between the groups (P = 0.056, P
= 0.233, P = 0.582, P = 0.798, P = 0.711, P =
0.859, P = 0.634, P = 1, P = 1,P = 1, P = 1,and
P = 1, respectively).
Spontaneous vaginal delivery, necessity
for emergency cesarean delivery, postpartum hemorrhage, abnormal hemorrhage during cesarean, necessity for
blood transfusion, and postpartum hysterectomy rates did not differ between the
groups (P =
0.530, P = 0.752, P
<0.001, P<0.001, P = 0.758, P = 1, P =
1,and P = 1, respectively)
. Despite being within normal limits, discharge time
after C/S and spontaneous vaginal delivery was
longer in the gestational thrombocytopenia group than in the control group.









Conclusions: The
results of the study showed that gestational thrombocytopenia did not pose a
risk for both the mother and the fetus in low-risk pregnancies.

References

  • Referances1. Burrows RF, Kelton JG. Fetal thrombocytopenia and its relation to maternal thrombocytopenia. N Engl J Med. 1993;329(20):1463-6.
  • Referances2. Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010;115(2):168-86.
  • Referances3. Gernsheimer T, James AH, Stasi R. How I treat thrombocytopenia in pregnancy. Blood. 2013;121(1):38-47.
  • Referances4. Boehlen F, Hohlfeld P, Extermann P, Perneger TV, de Moerloose P. Platelet count at term pregnancy: a reappraisal of the threshold. Obstetrics and gynecology. 2000;95(1):29-33.
  • Referances5. Sainio S, Kekomaki R, Riikonen S, Teramo K. Maternal thrombocytopenia at term: a population-based study. Acta obstetricia et gynecologica Scandinavica. 2000;79(9):744-9.
  • Referances6. Ruggeri M, Schiavotto C, Castaman G, Tosetto A, Rodeghiero F. Gestational thrombocytopenia: a prospective study. Haematologica. 1997;82(3):341-2.
  • Referances7. Wang X, Xu Y, Luo W, Feng H, Luo Y, Wang Y, et al. Thrombocytopenia in pregnancy with different diagnoses: Differential clinical features, treatments, and outcomes. Medicine. 2017;96(29):e7561.
  • Referances8. American College of O, Gynecologists' Committee on Practice B-O. Practice Bulletin No. 166: Thrombocytopenia in Pregnancy. Obstetrics and gynecology. 2016;128(3):e43-53.
  • Referances9. Sahin E, Madendag Y, Tayyar AT, Sahin ME, Col Madendag I, Acmaz G, et al. Perinatal outcomes in uncomplicated late preterm pregnancies with borderline oligohydramnios. J Matern Fetal Neonatal Med. 2017:1-4.
  • Referances10. Lin YH, Lo LM, Hsieh CC, Chiu TH, Hsieh TT, Hung TH. Perinatal outcome in normal pregnant women with incidental thrombocytopenia at delivery. Taiwan J Obstet Gynecol. 2013;52(3):347-50.
  • Referances11. Levy JA, Murphy LD. Thrombocytopenia in pregnancy. The Journal of the American Board of Family Practice. 2002;15(4):290-7.
  • Referances 12. http://www.tuik.gov.tr/PreHaberBultenleri.do?id=27588
There are 12 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Surgical Science Research Articles
Authors

Mefkure Eraslan Şahin

Erdem Şahin 0000-0001-9492-6223

Yusuf Madendağ 0000-0002-7622-2991

İlknur Çöl Madendağ

Gökhan Açmaz

Publication Date September 30, 2019
Acceptance Date September 26, 2019
Published in Issue Year 2019Volume: 41 Issue: 3

Cite

AMA Eraslan Şahin M, Şahin E, Madendağ Y, Çöl Madendağ İ, Açmaz G. Effect of gestational thrombocytopenia on negative fetal and maternal outcomes in low-risk pregnancies. CMJ. September 2019;41(3):620-625. doi:10.7197/cmj.vi.475431