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Year 2021, Volume: 43 Issue: 2, 124 - 133, 01.07.2021

Aynur Engin , Sevil Ceyhan Doğan , Mürşit Hasbek

https://doi.org/10.7197/cmj.870627

Abstract

Supporting Institution

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References

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Demographic, clinical, laboratory, radiological, and outcome features of possible and definitive COVID-19 patients followed in Sivas Cumhuriyet University Pandemic Clinic, in Turkey

Year 2021, Volume: 43 Issue: 2, 124 - 133, 01.07.2021

Aynur Engin , Sevil Ceyhan Doğan , Mürşit Hasbek

https://doi.org/10.7197/cmj.870627

Abstract

Objective: The aim of this study is to evaluate the epidemiological, clinical, laboratory, and radiological characteristics of 63 possible and definite COVID-19 patients who were followed up and treated in Sivas Cumhuriyet University Pandemic Clinic in April and May, 2020.
Method: In this retrospective study, the diagnosis and treatment of the patients were made according to the Turkish Ministry of Health COVID-19 guidelines. Patients' age, gender, underlying diseases, routine blood tests, SARS-CoV-2 PCR test results, clinical characteristics, treatments and radiological findings of the patients were taken from the patient files.
Results: The age range of 63 patients was 18-87 years, and the mean age was 43 years. 37 patients (58.7%) were male, and 26 (41.3%) were female. 25 patients had positive PCR test for SARS CoV-2. PCR negativity developed on the 3rd day at the earliest and the 20th day at the latest, with an average of 10 days. In 2 patients, the fluctuation was observed in the process of negativity of the PCR test. It was seen that the most complaint was cough and second one was shortness of breath. It was remarkable that most of our patients did not have a high fever. Of the patients, the mean white blood cell count was 6,663 and the neutrophil/lymphocyte ratio was average 2.25. In 49 patients (77.8%), lung lesions were detected with chest CT. The most common finding we detected with chest CT was bilateral multiple ground-glass areas. Hydroxychloroquine treatment was given to 90% of the patients. In addition to the standard treatment, 3.1% of the patients were given Favipiravir treatment.
Conclusions: In this study, epidemiological, clinical, laboratory and radiological characteristics of 63 COVID-19 cases followed in Sivas province were reported. Global collaboration and sharing data and experiences on COVID-19 is essential to managing the current pandemic process in the world.

Keywords

covid 19 , clinical feature, case , Sivas , Turkey

References

  • 1. Demirbilek Y, Pehlivantürk G, Ozgüler ZO, Alp Mese E. COVID-19 outbreak control, example of ministry of health of Turkey. Turk J Med Sci 2020;50:489-494.
  • 2. World Health Organization. Weekly epidemiological update - 27 January 2021. Available from: https://www.who.int/publications/m/item/weekly-epidemiological-update---27-january-2021 (Accessed January 29, 2021).
  • 3. The Turkish Ministry of Health, General Directorate of Public Health. COVID-19 (SARS-CoV-2 infection) Guide. Scientific Committee Study, 14 April 2020. (In Turkish: T. C. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü. COVID-19 (SARS-CoV-2 enfeksiyonu) rehberi, Bilim Kurulu Çalışması, 14 Nisan 2020). Available from: https://www.fip.org/files/content/priority-areas/coronavirus/mo-resources/Turkey_SARSCoV2InfectionGuide.pdf (Accessed October 19, 2020).
  • 4. World Health Organization. Clinical management of severe acute respiratory infection (‎‎‎SARI)‎‎‎ when COVID-19 disease is suspected: interim guidance, 13 March 2020. Available from: https://apps.who.int/iris/handle/10665/331446 (Accessed October 19, 2020).
  • 5. The Turkish Ministry of Health, COVID-19 Information Page (Sağlık Bakanlığı COVID-19 Bilgilendirme Sayfası). Available from: https://covid19.saglik.gov.tr (Accessed January 29, 2021).
  • 6. Cento V, Colagrossi L, Nava A, et al. Persistent positivity and fluctuations of SARS-CoV-2 RNA in clinically-recovered COVID-19 patients. J Infect 2020;81(3):e90-e92.
  • 7. Li Y, Yao L, Li J, et al. Stability issues of RT-PCR testing of SARS-CoV-2 for hospitalized patients clinically diagnosed with COVID-19. J Med Virol 2020;92(7):903-908.
  • 8. Wan S, Li M, Ye Z, et al. CT Manifestations and Clinical Characteristics of 1115 Patients with Coronavirus Disease 2019 (COVID-19): A Systematic Review and Meta-analysis. Acad Radiol 2020;27(7):910-921.
  • 9. Li LQ, Huang T, Wang YQ, et al. COVID-19 patients' clinical characteristics, discharge rate, and fatality rate of meta-analysis. J Med Virol 2020;92(6):577-583.
  • 10. Wei XS, Wang X, Niu YR, et al. Diarrhea Is Associated With Prolonged Symptoms and Viral Carriage in Corona Virus Disease 2019. Clin Gastroenterol Hepatol 2020;18(8):1753-1759.e2.
  • 11. Li XY, Dai WJ, Wu SN, Yang XZ, Wang HG. The occurrence of diarrhea in COVID-19 patients. Clin Res Hepatol Gastroenterol 2020;44(3):284-285.
  • 12. Sümer S, Ural O, Aktug-Demir N, et al. Clinical and laboratory characteristics of COVID-19 cases followed in Selcuk University Faculty of Medicine. Klimik Derg. 2020; 33(2): 122-7. Turkish.
  • 13. Mullol J, Alobid I, Mariño-Sánchez F, et al. The Loss of Smell and Taste in the COVID-19 Outbreak: a Tale of Many Countries. Curr Allergy Asthma Rep 2020;20(10):61.
  • 14. Roland LT, Gurrola JG 2nd, Loftus PA, Cheung SW, Chang JL. Smell and taste symptom-based predictive model for COVID-19 diagnosis. Int Forum Allergy Rhinol 2020;10(7):832-838.
  • 15. Ferrara G, Morgado-Carrasco D. Visual Dermatology: Acral Erythemato-purpuric Lesions During COVID-19 Pandemic. J Cutan Med Surg 2020;24(4):409.
  • 16. Sachdeva M, Gianotti R, Shah M, et al. Cutaneous manifestations of COVID-19: Report of three cases and a review of literature. J Dermatol Sci 2020;98(2):75-81.
  • 17. RECOVERY Collaborative Group, Horby P, Lim WS, Emberson JR, et al. Dexamethasone in Hospitalized Patients with Covid-19 - Preliminary Report. N Engl J Med 2020:NEJMoa2021436.
  • 18. COVID-19 Treatment Guidelines Panel. Coronavirus Disease 2019 (COVID-19) Treatment Guidelines. National Institutes of Health. Available from: https://www.covid19treatmentguidelines.nih.gov/ (Accessed October 19, 2020).
  • 19. The Turkish Ministry of Health, General Directorate of Public Health. COVID-19 (SARS-CoV-2 infection) Adult Patient Treatment. Scientific Committee Study, 09 October 2020. [In Turkish: T. C. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü. COVID-19 (SARS-CoV-2 enfeksiyonu), Erişkin Hasta Tedavisi. Bilim Kurulu Çalışması, 09 Ekim 2020]. Available from: https://covid19.saglik.gov.tr/TR-66926/eriskin-hasta-tedavisi.html (Accessed October 18, 2020).
There are 19 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Medical Science Research Articles
Authors

Aynur Engin 0000-0002-8533-8793

Sevil Ceyhan Doğan 0000-0003-1570-8848

Mürşit Hasbek 0000-0002-5217-8607

Publication Date July 1, 2021
Acceptance Date May 28, 2021
Published in Issue Year 2021Volume: 43 Issue: 2

Cite

AMA Engin A, Ceyhan Doğan S, Hasbek M. Demographic, clinical, laboratory, radiological, and outcome features of possible and definitive COVID-19 patients followed in Sivas Cumhuriyet University Pandemic Clinic, in Turkey. CMJ. July 2021;43(2):124-133. doi:10.7197/cmj.870627