Benign ve malign endometriyal patolojilerin klinik ve demografik özelliklerinin karşılaştırılması

Aim. The objective of this study is to compare clinical and demographic data of benign and malign pathologies of endometrium and to describe risc factors for endomatrial carcinoma. Method. Eighty-eight patients which was hysterectomised in our clinic between 2006 and 2010 was included. Twenty eight of these has the diagnosis as ‘proliferative endometrium’, twenty nine as ‘hyperplasia of endometrium’, thirty-one as ‘endometrioid type of endometrial carcinoma’. Data were collected from patient files retrospectively. Results. Pregnancy and parity rate, presence of diabetes mellitus and smoking were not altered for groups. Endometrial thickness and presence of hypertension were significantly higher for carcinoma group. Endometrial carcinoma patients were generally postmenauposal and had younger menarche age. Discussion. Advanced age, early menarche, increased endometrial thickness, hypertension and postmenapouse are risk factors for endometrial carcinoma.

Özet

Amaç. Bu çalışma endometriyum kanseri ve benign endometriyal patolojilerin klinik ve demografik verilerini karşılaştırmayı ve endometriyum kanseri için risk faktörlerini belirlemeyi amaçlamaktadır. Yöntem. Kliniğimizde 2006-2010 yılları arasında endometrioid tip endometrial karsinom tanısı almış 31, endometriyal hiperplazi tanısı almış 29 ve proliferatif endometriyum tanısı almış 28 olmak üzere toplam 88 histerektomi olgusu çalışmaya dahil edildi. Olguların demografik ve takip bilgileri klinik dosyalarından elde edildi. Bulgular. Gebelik ve parite sayısı, diyabet varlığı ve sigara kullanımı arasında fark bulunamazken; ortalama yaş, endometriyal kalınlık değeri, menarş yaşı, postmenapozal olmak ve hipertansiyon varlığı endometriyum kanseri grubunda farklı bulunmuştur. Sonuç. Endometriyum kanseri hastaları daha erken yaşta menarş görmektedir ve çoğu postmenapozaldir İleri yaş, artmış endometriyal kalınlık ve hipertansiyon endometriyum kanseri için diğer risk faktörleridir.

Anahtar sözcükler: Endometriyum kanseri, risk faktörleri

 

Abstract

Aim. The objective of this study is to compare clinical and demographic data of benign and malign pathologies of endometrium and to describe risc factors for endomatrial carcinoma. Method. Eighty-eight patients which was hysterectomised in our clinic between 2006 and 2010 was included. Twenty eight of these has the diagnosis as ‘proliferative endometrium’, twenty nine as ‘hyperplasia of endometrium’, thirty-one as ‘endometrioid type of endometrial carcinoma’. Data were collected from patient files retrospectively. Results. Pregnancy and parity rate, presence of diabetes mellitus and smoking were not altered for groups. Endometrial thickness and presence of hypertension were significantly higher for carcinoma group. Endometrial carcinoma patients were generally postmenauposal and had younger menarche age. Discussion. Advanced age, early menarche, increased endometrial thickness, hypertension and postmenapouse are risk factors for endometrial carcinoma.

Keywords: Endometrial carcinoma, risk factors