Öz
Kaynakça
- Referances1. Burrows RF, Kelton JG. Fetal thrombocytopenia and its relation to maternal thrombocytopenia. N Engl J Med. 1993;329(20):1463-6.
- Referances2. Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010;115(2):168-86.
- Referances3. Gernsheimer T, James AH, Stasi R. How I treat thrombocytopenia in pregnancy. Blood. 2013;121(1):38-47.
- Referances4. Boehlen F, Hohlfeld P, Extermann P, Perneger TV, de Moerloose P. Platelet count at term pregnancy: a reappraisal of the threshold. Obstetrics and gynecology. 2000;95(1):29-33.
- Referances5. Sainio S, Kekomaki R, Riikonen S, Teramo K. Maternal thrombocytopenia at term: a population-based study. Acta obstetricia et gynecologica Scandinavica. 2000;79(9):744-9.
- Referances6. Ruggeri M, Schiavotto C, Castaman G, Tosetto A, Rodeghiero F. Gestational thrombocytopenia: a prospective study. Haematologica. 1997;82(3):341-2.
- Referances7. Wang X, Xu Y, Luo W, Feng H, Luo Y, Wang Y, et al. Thrombocytopenia in pregnancy with different diagnoses: Differential clinical features, treatments, and outcomes. Medicine. 2017;96(29):e7561.
- Referances8. American College of O, Gynecologists' Committee on Practice B-O. Practice Bulletin No. 166: Thrombocytopenia in Pregnancy. Obstetrics and gynecology. 2016;128(3):e43-53.
- Referances9. Sahin E, Madendag Y, Tayyar AT, Sahin ME, Col Madendag I, Acmaz G, et al. Perinatal outcomes in uncomplicated late preterm pregnancies with borderline oligohydramnios. J Matern Fetal Neonatal Med. 2017:1-4.
- Referances10. Lin YH, Lo LM, Hsieh CC, Chiu TH, Hsieh TT, Hung TH. Perinatal outcome in normal pregnant women with incidental thrombocytopenia at delivery. Taiwan J Obstet Gynecol. 2013;52(3):347-50.
- Referances11. Levy JA, Murphy LD. Thrombocytopenia in pregnancy. The Journal of the American Board of Family Practice. 2002;15(4):290-7.
- Referances 12. http://www.tuik.gov.tr/PreHaberBultenleri.do?id=27588
Effect of gestational thrombocytopenia on negative fetal and maternal outcomes in low-risk pregnancies
Öz
Objective: Thrombocytopenia,
expressed as platelet counts lower than 150 × 109 /L, is a common
hematological anomaly seen in 6.6% of the pregnancies. Incidental
thrombocytopenia of the pregnancy, commonly referred
to as gestational thrombocytopenia, accounts for 70%–80% of cases.
This study aimed
to elucidate the effect of gestational thrombocytopenia on negative fetal and
maternal results in low-risk pregnancies.
Method: The
patients were divided into two groups. The control group (n = 240) consisted of healthy pregnant women with normal platelet
count, and the study group (n = 80) consisted of pregnant women with
gestational thrombocytopenia.
Results: Maternal age,
pre-pregnancy body mass indexes, parity, and previous cesarean history rates
were similar in both groups. Gestational age during delivery, fetal weight, delivery
induction, amniotic fluid stained with meconium, hyperbilirubinemia, admission
to neonatal intensive care unit, transient
tachypnea of the newborn, respiratory distress syndrome, hypoxic–ischemic encephalopathy, necrotizing
enterocolitis, intraventricular hemorrhage, and 5-min Apgar scores of <7 were not different between the groups (P = 0.056, P
= 0.233, P = 0.582, P = 0.798, P = 0.711, P =
0.859, P = 0.634, P = 1, P = 1,P = 1, P = 1,and
P = 1, respectively). Spontaneous vaginal delivery, necessity
for emergency cesarean delivery, postpartum hemorrhage, abnormal hemorrhage during cesarean, necessity for
blood transfusion, and postpartum hysterectomy rates did not differ between the
groups (P =
0.530, P = 0.752, P<0.001, P<0.001, P = 0.758, P = 1, P =
1,and P = 1, respectively). Despite being within normal limits, discharge time
after C/S and spontaneous vaginal delivery was
longer in the gestational thrombocytopenia group than in the control group.
Conclusions: The
results of the study showed that gestational thrombocytopenia did not pose a
risk for both the mother and the fetus in low-risk pregnancies.
Anahtar Kelimeler
Gestational thrombocytopenia negative fetal outcome negative maternal outcome
Kaynakça
- Referances1. Burrows RF, Kelton JG. Fetal thrombocytopenia and its relation to maternal thrombocytopenia. N Engl J Med. 1993;329(20):1463-6.
- Referances2. Provan D, Stasi R, Newland AC, Blanchette VS, Bolton-Maggs P, Bussel JB, et al. International consensus report on the investigation and management of primary immune thrombocytopenia. Blood. 2010;115(2):168-86.
- Referances3. Gernsheimer T, James AH, Stasi R. How I treat thrombocytopenia in pregnancy. Blood. 2013;121(1):38-47.
- Referances4. Boehlen F, Hohlfeld P, Extermann P, Perneger TV, de Moerloose P. Platelet count at term pregnancy: a reappraisal of the threshold. Obstetrics and gynecology. 2000;95(1):29-33.
- Referances5. Sainio S, Kekomaki R, Riikonen S, Teramo K. Maternal thrombocytopenia at term: a population-based study. Acta obstetricia et gynecologica Scandinavica. 2000;79(9):744-9.
- Referances6. Ruggeri M, Schiavotto C, Castaman G, Tosetto A, Rodeghiero F. Gestational thrombocytopenia: a prospective study. Haematologica. 1997;82(3):341-2.
- Referances7. Wang X, Xu Y, Luo W, Feng H, Luo Y, Wang Y, et al. Thrombocytopenia in pregnancy with different diagnoses: Differential clinical features, treatments, and outcomes. Medicine. 2017;96(29):e7561.
- Referances8. American College of O, Gynecologists' Committee on Practice B-O. Practice Bulletin No. 166: Thrombocytopenia in Pregnancy. Obstetrics and gynecology. 2016;128(3):e43-53.
- Referances9. Sahin E, Madendag Y, Tayyar AT, Sahin ME, Col Madendag I, Acmaz G, et al. Perinatal outcomes in uncomplicated late preterm pregnancies with borderline oligohydramnios. J Matern Fetal Neonatal Med. 2017:1-4.
- Referances10. Lin YH, Lo LM, Hsieh CC, Chiu TH, Hsieh TT, Hung TH. Perinatal outcome in normal pregnant women with incidental thrombocytopenia at delivery. Taiwan J Obstet Gynecol. 2013;52(3):347-50.
- Referances11. Levy JA, Murphy LD. Thrombocytopenia in pregnancy. The Journal of the American Board of Family Practice. 2002;15(4):290-7.
- Referances 12. http://www.tuik.gov.tr/PreHaberBultenleri.do?id=27588
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Konular | Sağlık Kurumları Yönetimi |
| Bölüm | Surgical Science Research Makaleler |
| Yazarlar | |
| Yayımlanma Tarihi | 30 Eylül 2019 |
| Kabul Tarihi | 26 Eylül 2019 |
| Yayımlandığı Sayı | Yıl 2019Cilt: 41 Sayı: 3 |