Öz
Abstract
Placental site nodule, developing from intermediate trophoblasts, is a rare benign lesion. Although it is a benign lesion, it’s histopathological differential diagnosis from placental site trophoblastic tumor and epithelioid trophoblastic tumor which are aggressive lesions of the intermediate trophoblasts, and non-trophoblastic neoplasms such as squamous cell carcinoma, is important due to its histological appearance. In our report, placental site nodule diagnosed in 33-year-old, female patient who was suffering from intermittant menometrorrhagia and had a diagnostic curettage is presented.
Keywords: Placental site nodule, intermediate trophoblasts, abnormal uterine bleeding
Özet
Plasental bölge nodülü intermediate trofoblastlardan gelişen nadir görülen benign bir lezyondur.Benign bir lezyon olmasına rağmen histolojik görünümü nedeniyle intermediate trofoblastların agresif lezyonları olan plasental bölge neoplastik tümörü ve epiteloid trofoblastik tümör ile skuamoz hücreli karsinom gibi trofoblastik olmayan neoplazilerden histopatolojik ayrımı önemlidir.Bu makalede intermitan menometroraji şikayeti ile başvurup tanısal küretaj yapılan ve plasental bölge nodülü tanısı alan 33 yaşında bir bayan hasta sunulmuştur.
Anahtar sözcükler: Plasental bölge nodülü, intermediate trofoblastlar, anormal uterin kanama
Anahtar Kelimeler
Kaynakça
- Jacob S, Mohapatra D. Placental site nodule: a tumor-like trophoblastic lesion. Indian J Pathol Microbiol 2009; 52: 240-1.
- O'Neill CJ, Cook I, McCluggage WG. Postcesarean delivery uterine diffuse intermediate trophoblastic lesion resembling placental site plaque. Hum Pathol 2009; 40: 1358-60.
- Shih IM, Kurman RJ. The pathology of intermediate trophoblastic tumors and tumor-like lesions. Int J Gynecol Pathol 2001; 20: 31-47.
- Young RH, Kurman RJ, Scully RE. Placental site nodules and plaques. A clinicopathologic analysis of 20 cases. Am J Surg Pathol 1990; 14: 1001-9.
- Huettner PC, Gersell DJ. Placental site nodule: a clinicopathologic study of 38 cases. Int J Gynecol Pathol 1994; 13: 191-8.
- Stolnicu S, Radulescu D, González-Rocha T, Timar I, Puscasiu L, Nogales FF. Exaggerated placental site lesion with unusual presentation in the cervix of a perimenopausal patient. APMIS 2008; 116:160-2.
- Kurman RJ. The morphology, biology, and pathology of intermediate trophoblast: a look back to the present. Hum Pathol 1991; 22: 847-55.
- Shih IM, Seidman JD, Kurman RJ. Placental site nodule and characterization of distinctive types of intermediate trophoblast. Hum Pathol 1999; 30: 687-94.
- Lee KC, Chan JK. Placental site nodule. Histopathology 1990; 16: 193-5.
- Van Dorpe J, Moerman P. Placental site nodule of the uterine cervix. Histopathology 1996; 29: 379-82.
- Al-Hussaini M, Lioe TF, McCluggage WG. Placental site nodule of the ovary. Histopathology 2002; 41: 471-2.
- Campello TR, Fittipaldi H, O'Valle F, Carvia RE, Nogales FF. Extrauterine (tubal) placental site nodule. Histopathology 1998; 32: 562-5.
- Nayar R, Snell J, Silverberg SG, Lage JM. Placental site nodule occurring in a fallopian tube. Hum Pathol 1996; 27: 1243-5.
- Shitabata PK, Rutgers JL. The placental site nodule: an immunohistochemical study. Hum Pathol 1994; 25: 1295-301.
- Collins RJ, Ngan HY, Wong LC. Placental site trophoblastic tumor: with features between an exaggerated placental site reaction and a placental site trophoblastic tumor. Int J Gynecol Pathol 1990; 9: 170-7.
Öz
Plasental bölge nodülü intermediate trofoblastlardan gelişen nadir görülen benign bir lezyondur. Benign bir lezyon olmasına rağmen histolojik görünümü nedeniyle intermediate trofoblastların agresif lezyonları olan plasental bölge neoplastik tümörü ve epiteloid trofoblastik tümör ile skuamoz hücreli karsinom gibi trofoblastik olmayan neoplazilerden histopatolojik ayrımı önemlidir.Bu makalede intermitan menometroraji şikayeti ile başvurup tanısal küretaj yapılan ve plasental bölge nodülü tanısı alan 33 yaşında bir bayan hasta sunulmuştur
Anahtar Kelimeler
Plasental bölge nodülü intermediate trofoblastlar anormal uterin kanama
Kaynakça
- Jacob S, Mohapatra D. Placental site nodule: a tumor-like trophoblastic lesion. Indian J Pathol Microbiol 2009; 52: 240-1.
- O'Neill CJ, Cook I, McCluggage WG. Postcesarean delivery uterine diffuse intermediate trophoblastic lesion resembling placental site plaque. Hum Pathol 2009; 40: 1358-60.
- Shih IM, Kurman RJ. The pathology of intermediate trophoblastic tumors and tumor-like lesions. Int J Gynecol Pathol 2001; 20: 31-47.
- Young RH, Kurman RJ, Scully RE. Placental site nodules and plaques. A clinicopathologic analysis of 20 cases. Am J Surg Pathol 1990; 14: 1001-9.
- Huettner PC, Gersell DJ. Placental site nodule: a clinicopathologic study of 38 cases. Int J Gynecol Pathol 1994; 13: 191-8.
- Stolnicu S, Radulescu D, González-Rocha T, Timar I, Puscasiu L, Nogales FF. Exaggerated placental site lesion with unusual presentation in the cervix of a perimenopausal patient. APMIS 2008; 116:160-2.
- Kurman RJ. The morphology, biology, and pathology of intermediate trophoblast: a look back to the present. Hum Pathol 1991; 22: 847-55.
- Shih IM, Seidman JD, Kurman RJ. Placental site nodule and characterization of distinctive types of intermediate trophoblast. Hum Pathol 1999; 30: 687-94.
- Lee KC, Chan JK. Placental site nodule. Histopathology 1990; 16: 193-5.
- Van Dorpe J, Moerman P. Placental site nodule of the uterine cervix. Histopathology 1996; 29: 379-82.
- Al-Hussaini M, Lioe TF, McCluggage WG. Placental site nodule of the ovary. Histopathology 2002; 41: 471-2.
- Campello TR, Fittipaldi H, O'Valle F, Carvia RE, Nogales FF. Extrauterine (tubal) placental site nodule. Histopathology 1998; 32: 562-5.
- Nayar R, Snell J, Silverberg SG, Lage JM. Placental site nodule occurring in a fallopian tube. Hum Pathol 1996; 27: 1243-5.
- Shitabata PK, Rutgers JL. The placental site nodule: an immunohistochemical study. Hum Pathol 1994; 25: 1295-301.
- Collins RJ, Ngan HY, Wong LC. Placental site trophoblastic tumor: with features between an exaggerated placental site reaction and a placental site trophoblastic tumor. Int J Gynecol Pathol 1990; 9: 170-7.
Ayrıntılar
| Birincil Dil | İngilizce |
|---|---|
| Bölüm | Olgu Sunumları |
| Yazarlar | |
| Yayımlanma Tarihi | 21 Haziran 2012 |
| Yayımlandığı Sayı | Yıl 2012Cilt: 34 Sayı: 2 |